It depends on the type of vaccine. Some live attenuated vaccines could potentially cause post-vaccination shedding of the virus to susceptible persons, requiring extra precautions to be taken; whereas inactivated viruses cannot replicate, because they are considered dead viruses and are unable to cause post-vaccination shedding of the virus. Other vaccines may not include the actual virus. Prior to having a provider personally participate in any clinical vaccine trial, we recommend that the practice review the manufacturers’ vaccine information and consent agreement related to the trial to determine if any precautions need to be taken post-vaccination.
In addition, the potential side effects to the vaccine mimic COVID-19 symptoms. Caution will need to be utilized to avoid missing a possible infection. A vaccine participant must follow practice policy and quarantine if they develop symptoms until COVID-19 is ruled out. Participants should not assume symptoms are side effects and not COVID-19.
We also recommend that practices maintain documentation of vaccine trial participation information, such as a copy of the vaccine trial consent, requirements, and precautions recommended to support that appropriate measures were taken by the practice and the participating individual. Any participating employees should alert practice mangers of any risk or concerns noted post-vaccination.